Print view
 

Studies Yield ‘Impressive’ Results in Fight Against Cystic Fibrosis

“These findings indicate that it may soon be possible to offer safe and effective molecularly targeted therapies to 90 percent of persons with cystic fibrosis,” wrote the director, Dr. Francis S. Collins, who led the team that in 1989 identified the gene that causes the genetic disease affecting the lungs and digestive system. “This should be a cause for major celebration,” he wrote in the Thursday editorial.

The two studies, published by The New England Journal of Medicine and The Lancet, describe the results of clinical trials of a three-drug therapy for people with cystic fibrosis, which causes thick mucus to build up in the lungs and other parts of the body and drastically shortens life expectancy. Both studies found that, among other things, patients who received the therapy showed improvement in a key measure of lung capacity, findings that Dr. Collins described in a separate N.I.H. blog post as “striking.”

The studies were conducted with funding from Vertex Pharmaceuticals, which developed the triple-combination drug therapy, known as Trikafta. Last week, the Food and Drug Administration approved Trikafta for use with about 90 percent of patients with cystic fibrosis — those who have the most common cystic fibrosis gene mutation and are 12 or older.

Read the full aricle here.

Autor: Niraj Chokshi   Quelle: The New York Times, 04.11.2019
"Going International promotes access to education and training for all regardless of social, geographic and national borders."
Weitere News
Emerging respiratory viruses, including nCoV: methods for detection, prevention, response and control
Watch the GAP! A critical civil society perspective on the “Global Action Plan for Healthy Lives and Well-Being for All”
ESTHER Switzerland Call for Proposals 2020
Evidence-based toolkit offers solutions to improve environment, health, and reduce inequalities
Public health emergencies occurring in the WHO African Region
Catalysing Change for Gender Equality
TMW Center launches bilingual resources to advance brain development for children
Short sleep may harm bone health in older women
Human Trafficking – It Came Disguised as the Opportunity of a Lifetime
Study finds functional medicine model is associated with improvements in health-related QOL
NHS treating 5,000 diabetics a day as one in 10 patients now suffer with illness, figures reveal
Bangladesh’s Climate Change Victims Safeguard the Sundarbans’ Endangered Dolphins
European Health Leadership Award 2019
Wall Street can Free the World’s 40 Million Modern-Day Slaves
Financing Health Promoting Services
One person dies by suicide every 40 seconds: new UN health agency report
One person dies by suicide every 40 seconds: new UN health agency report
A ‘Cure’ for Ebola but Will it Stop the Outbreak if People Won’t Get Treatment?
The Role of Women’s Organisations in Crisis-Settings
Statement on World Day against Trafficking in Persons
Vaccine Fast Facts
CRA shortage is worsening while demand grows – a vicious circle which opens masses of job opportunities
Why Doctors Hate Their Computers
Junior hospital doctors
90–90–90 Treatment for All
Incident Management System
Incident Management System
An Economy for the 99%
European Virus Archive goes global
Establishing a Global Vaccine-Development Fund

Newsletter Sign Up

 

Österreichische Akademie der ÄrzteAnästhesie in Entwicklungsländern e. V.AGEM - Arbeitsgemeinschaft Ethnologie und MedizinCenter of ExcellenceÄrzte der WeltOÖ Gebietskrankenkasse, Referat für Wissenschaftskooperation Centro per la Formazione Permanente e l'Aggiornamento del Personale del Servizio SanitarionewTree